Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 55
Filtrar
1.
J Trauma Nurs ; 29(6): 330-334, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36350173

RESUMEN

BACKGROUND: Traumatic injuries resulting from personal watercraft hydrostatic jets are expected to increase as personal watercrafts are affordable, portable, and used in an increasingly wide range of locales. CASE PRESENTATION: This case study presents an unusual severe perineal injury in a 17-year-old adolescent girl resulting from a fall from a personal watercraft and contact with the vehicle's hydrostatic jet. This case report provides an overview of the mechanism, treatment, and prevention of personal watercraft injuries. CONCLUSION: Knowledge of this mechanism's potential for serious morbidity and mortality, patient assessment and management principles, and injury prevention strategies are essential to providing effective trauma center care.


Asunto(s)
Accidentes por Caídas , Adolescente , Femenino , Humanos
2.
BMC Med Educ ; 22(1): 69, 2022 Jan 29.
Artículo en Inglés | MEDLINE | ID: mdl-35093052

RESUMEN

BACKGROUND: International medical graduates (IMGs) have less burnout than U. S. medical school graduates (USMGs) during residency training. This study evaluates possible correlates of differences in burnout rates between USMGs and IMGs. METHODS: We surveyed 375 first-year residents at orientation in June/July 2017. We assessed burnout using the Copenhagen Burnout Inventory (CBI) and used validated scales to measure stress, quality of life (QoL), mastery, and spirituality. We collected data on gender, place of graduation, language fluency, and specialty. We compared CBI scores between USMGs and IMGs, performed a multivariate linear regression analysis of relationships between covariates and CBI subscales, and logistic regression analysis for our categorical definition of burnout. RESULTS: Two hundred twenty-two residents responded for a response rate of 59%. Personal, work or patient- related burnout was common among residents, particularly among USMGs. The most common form of burnout was work-related. Forty nine percent of USMGs have work burnout compared to 26% of IMGs (p < 0.01). In multivariate analysis, being an IMG reduced odds of work-related and of total burnout by 50% (OR 0.5 C.I 0.25-0.99). Perceived mastery was associated with reductions in all subscales of burnout (p < 0.05). Stress and low QoL related to personal and work burnout scores (p < 0.01). CONCLUSION: Work-related burnout is more common among USMGs than in IMGs. Although mastery, QoL and stress were correlates of burnout among all residents, these factors did not explain the difference. Future studies should evaluate the role of medical school structure and curriculum on differences in burnout rates between the two groups.


Asunto(s)
Agotamiento Profesional , Internado y Residencia , Agotamiento Profesional/epidemiología , Humanos , Calidad de Vida , Facultades de Medicina , Encuestas y Cuestionarios
3.
AACN Adv Crit Care ; 29(3): 259-267, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-30185492

RESUMEN

BACKGROUND: Limited resources and increased patient care demands have strained nurse-physician relationships in our hospital's neurosurgical intensive care unit, leading to low morale and adversarial dynamics. Studies exploring benefits of coaching interprofessional teamwork demonstrate performance improvements. Therefore, a coaching program designed to improve nurse-physician teamwork was initiated by the neurosurgery department of the hospital's affiliated university. OBJECTIVE: To assess the impact of a coaching program for nurses and physicians on workplace performance in a neurosurgical intensive care unit at a level 1 trauma center. METHODS: A coach was incorporated into everyday activities on the neurosurgical unit. After 3 months of observations, specific interdisciplinary initiatives were implemented to foster a more positive workplace environment. Nurses' perceptions before and after the initiatives were measured and compared using appropriate statistical tools. RESULTS: A significant improvement in relationships was found in 6 of 7 targeted categories after the program had been in place for 5 months. The results were sustained at 1 year. CONCLUSION: A coaching program is an effective method of improving nurse-physician relationships, leading to enhanced workplace performance.


Asunto(s)
Tutoría/métodos , Mentores/psicología , Personal de Enfermería en Hospital/educación , Personal de Enfermería en Hospital/psicología , Relaciones Médico-Enfermero , Lugar de Trabajo/psicología , Adulto , Actitud del Personal de Salud , Comunicación , Femenino , Humanos , Masculino , Persona de Mediana Edad , Cultura Organizacional
5.
PLoS One ; 10(8): e0134038, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26241650

RESUMEN

BACKGROUND: Decision-making relies on both analytical and emotional thinking. Cognitive reasoning styles (e.g. maximizing and satisficing tendencies) heavily influence analytical processes, while affective processes are often dependent on regret. The relationship between regret and cognitive reasoning styles has not been well studied in physicians, and is the focus of this paper. METHODS: A regret questionnaire and 6 scales measuring individual differences in cognitive styles (maximizing-satisficing tendencies; analytical vs. intuitive reasoning; need for cognition; intolerance toward ambiguity; objectivism; and cognitive reflection) were administered through a web-based survey to physicians of the University of South Florida. Bonferroni's adjustment was applied to the overall correlation analysis. The correlation analysis was also performed without Bonferroni's correction, given the strong theoretical rationale indicating the need for a separate hypothesis. We also conducted a multivariate regression analysis to identify the unique influence of predictors on regret. RESULTS: 165 trainees and 56 attending physicians (age range 25 to 69) participated in the survey. After bivariate analysis we found that maximizing tendency positively correlated with regret with respect to both decision difficulty (r=0.673; p<0.001) and alternate search strategy (r=0.239; p=0.002). When Bonferroni's correction was not applied, we also found a negative relationship between satisficing tendency and regret (r=-0.156; p=0.021). In trainees, but not faculty, regret negatively correlated with rational-analytical thinking (r=-0.422; p<0.001), need for cognition (r=-0.340; p<0.001), and objectivism (r=-0.309; p=0.003) and positively correlated with ambiguity intolerance (r=0.285; p=0.012). However, after conducting a multivariate regression analysis, we found that regret was positively associated with maximizing only with respect to decision difficulty (r=0.791; p<0.001), while it was negatively associated with satisficing (r=-0.257; p=0.020) and objectivism (r=-0.267; p=0.034). We found no statistically significant relationship between regret and overall accuracy on conditional inferential tasks. CONCLUSION: Regret in physicians is strongly associated with their tendency to maximize; i.e. the tendency to consider more choices among abundant options leads to more regret. However, physicians who exhibit satisficing tendency - the inclination to accept a "good enough" solution - feel less regret. Our observation that objectivism is a negative predictor of regret indicates that the tendency to seek and use empirical data in decision-making leads to less regret. Therefore, promotion of evidence-based reasoning may lead to lower regret.


Asunto(s)
Actitud del Personal de Salud , Emociones , Médicos/psicología , Pensamiento , Adulto , Anciano , Conducta de Elección , Toma de Decisiones , Empirismo , Medicina Basada en la Evidencia , Florida , Humanos , Persona de Mediana Edad , Modelos Psicológicos , Satisfacción Personal
6.
Int J Cancer ; 137(1): 204-11, 2015 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-25418440

RESUMEN

The majority of intermediate-risk rhabdomyosarcoma (RMS) patients have gross residual disease (Group III) after their first operative procedure. It is currently not known if local control rates can be maintained when, following induction chemotherapy, the radiation therapy (RT) dose is decreased after a delayed primary excision (DPE). To answer this question we evaluated patients enrolled on COG D9803 (1999-2005) who had Group III tumors of the bladder dome, extremity or trunk (thorax, abdomen and pelvis) were candidates for DPE at Week 12 if the primary tumor appeared resectable. RT dose was then adjusted by the completeness of DPE: no evidence of disease 36 Gy, microscopic residual 41.4 Gy and gross residual disease (GRD) 50.4 Gy. A total of 161 Group III patients were evaluated (24 bladder dome, 63 extremity and 74 trunk). Seventy-three patients (45%) underwent DPE which achieved removal of all gross disease in 61 (84%) who were then eligible for reduced RT dose (43/73 received 36 Gy, 19/73 received 41.4 Gy). The local 5-year failure rate (0% for bladder dome, 7% for extremity and 20% for trunk) was similar to IRS-IV, which did not encourage DPE and did not allow for DPE adapted RT dose reduction. In conclusion, DPE was performed in 45% of Group III RMS patients with tumors at select anatomic sites (bladder dome, extremity and trunk) and 84% of those who had DPE were eligible for RT dose reduction. Local control outcomes were similar to historic results with RT alone.


Asunto(s)
Abdomen/efectos de la radiación , Pelvis/efectos de la radiación , Rabdomiosarcoma/radioterapia , Rabdomiosarcoma/cirugía , Tórax/efectos de la radiación , Vejiga Urinaria/efectos de la radiación , Abdomen/patología , Niño , Preescolar , Ensayos Clínicos como Asunto , Terapia Combinada , Humanos , Lactante , Recién Nacido , Neoplasia Residual , Pelvis/patología , Dosificación Radioterapéutica , Rabdomiosarcoma/patología , Tórax/patología , Insuficiencia del Tratamiento , Vejiga Urinaria/patología
7.
Med Decis Making ; 34(5): 627-37, 2014 07.
Artículo en Inglés | MEDLINE | ID: mdl-24722474

RESUMEN

BACKGROUND: Patient outcomes critically depend on accuracy of physicians' judgment, yet little is known about individual differences in cognitive styles that underlie physicians' judgments. The objective of this study was to assess physicians' individual differences in cognitive styles relative to age, experience, and degree and type of training. METHODS: Physicians at different levels of training and career completed a web-based survey of 6 scales measuring individual differences in cognitive styles (maximizing v. satisficing, analytical v. intuitive reasoning, need for cognition, intolerance toward ambiguity, objectivism, and cognitive reflection). We measured psychometric properties (Cronbach's α) of scales; relationship of age, experience, degree, and type of training; responses to scales; and accuracy on conditional inference task. RESULTS: The study included 165 trainees and 56 attending physicians (median age 31 years; range 25-69 years). All 6 constructs showed acceptable psychometric properties. Surprisingly, we found significant negative correlation between age and satisficing (r = -0.239; P = 0.017). Maximizing (willingness to engage in alternative search strategy) also decreased with age (r = -0.220; P = 0.047). Number of incorrect inferences negatively correlated with satisficing (r = -0.246; P = 0.014). Disposition to suppress intuitive responses was associated with correct responses on 3 of 4 inferential tasks. Trainees showed a tendency to engage in analytical thinking (r = 0.265; P = 0.025), while attendings displayed inclination toward intuitive-experiential thinking (r = 0.427; P = 0.046). However, trainees performed worse on conditional inference task. CONCLUSION: Physicians capable of suppressing an immediate intuitive response to questions and those scoring higher on rational thinking made fewer inferential mistakes. We found a negative correlation between age and maximizing: Physicians who were more advanced in their careers were less willing to spend time and effort in an exhaustive search for solutions. However, they appeared to have maintained their "mindware" for effective problem solving.


Asunto(s)
Cognición , Juicio , Médicos/psicología , Adulto , Factores de Edad , Anciano , Femenino , Humanos , Internado y Residencia , Masculino , Persona de Mediana Edad , Psicometría
8.
Pediatr Surg Int ; 29(4): 401-5, 2013 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-23242202

RESUMEN

Pancreatic ductal injuries in children are rare, and ductal transections presenting in a delayed or subacute fashion are seldom reported. We describe two cases of traumatic pancreatic ductal transection secondary to physical abuse, both of which presented late to medical care. Both were managed successfully without pancreatic resection. Judicious application of non-resectional management can yield favorable outcomes in this subset of pediatric patients.


Asunto(s)
Maltrato a los Niños , Conductos Pancreáticos/lesiones , Preescolar , Pancreatocolangiografía por Resonancia Magnética , Quiste del Colédoco/etiología , Quiste del Colédoco/cirugía , Drenaje , Femenino , Humanos , Conductos Pancreáticos/diagnóstico por imagen , Fístula Pancreática/etiología , Seudoquiste Pancreático/etiología , Seudoquiste Pancreático/cirugía , Tomografía Computarizada por Rayos X
9.
J Am Coll Radiol ; 9(8): 545-53, 2012 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-22863462

RESUMEN

The appropriate imaging for pediatric patients (ages 0-5 years) being evaluated for limping depends on the clinical presentation, specifically, the presence of signs of infection, any localization of pain, and history of or suspected trauma. Common diagnoses causing limping in children are briefly reviewed, and recommended imaging techniques are discussed, including toddler's fracture, transient synovitis, septic arthritis, Legg-Calvé-Perthes disease, and osteomyelitis. The ACR Appropriateness Criteria(®) are evidence-based guidelines for specific clinical conditions that are reviewed every 2 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances in which evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.


Asunto(s)
Diagnóstico por Imagen/normas , Marcha , Trastornos del Movimiento/diagnóstico , Pediatría/normas , Guías de Práctica Clínica como Asunto , Radiología/normas , Niño , Preescolar , Diagnóstico Diferencial , Humanos , Lactante , Recién Nacido , Estados Unidos
10.
J Pediatr Surg ; 47(6): 1155-8, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-22703786

RESUMEN

The decision for aggressive reoperation after discovery of an appendiceal carcinoid is generally based upon criteria such as size, grade, degree of involvement of the mesoappendix or the appendiceal base, lymphovascular invasion, and the presence of goblet cell or adenocarcinoid features. No guidelines currently exist for the management of perforated appendiceal carcinoids. We present a case of perforated appendiceal carcinoid that was subsequently treated with right hemicolectomy, and we review the pertinent literature.


Asunto(s)
Neoplasias del Apéndice/complicaciones , Apendicitis/cirugía , Tumor Carcinoide/complicaciones , Colectomía/métodos , Perforación Intestinal/cirugía , Absceso Abdominal/complicaciones , Absceso Abdominal/cirugía , Adolescente , Apendicectomía , Neoplasias del Apéndice/diagnóstico , Neoplasias del Apéndice/patología , Neoplasias del Apéndice/cirugía , Neoplasias del Apéndice/orina , Apendicitis/etiología , Biomarcadores de Tumor/orina , Tumor Carcinoide/diagnóstico , Tumor Carcinoide/patología , Tumor Carcinoide/cirugía , Tumor Carcinoide/orina , Humanos , Ácido Hidroxiindolacético/orina , Hallazgos Incidentales , Perforación Intestinal/etiología , Laparoscopía , Escisión del Ganglio Linfático , Masculino , Invasividad Neoplásica , Estadificación de Neoplasias
11.
Rio de Janeiro; Elsevier; 3 ed; 2012. 599 p. ilus, tab.
Monografía en Portugués | Sec. Munic. Saúde SP, AHM-Acervo, TATUAPE-Acervo | ID: sms-9089
12.
J Am Coll Radiol ; 8(2): 87-94, 2011 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-21292182

RESUMEN

The appropriate imaging for pediatric patients being evaluated for suspected physical abuse depends on the age of the child, the presence of neurologic signs and symptoms, evidence of thoracic or abdominopelvic injuries, and whether the injuries are discrepant with the clinical history. The clinical presentations reviewed consider these factors and provide evidence-based consensus recommendations by the ACR Appropriateness Criteria(®) Expert Panel on Pediatric Imaging.


Asunto(s)
Maltrato a los Niños/clasificación , Maltrato a los Niños/prevención & control , Diagnóstico por Imagen/normas , Testimonio de Experto/normas , Medicina Legal/normas , Radiología/normas , Niño , Humanos , Estados Unidos
13.
Cancer ; 117(11): 2541-50, 2011 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-24048802

RESUMEN

BACKGROUND: The objectives of this study were to compare tumor volume and patient weight versus traditional factors of tumor size (greatest dimension) and patient age and to determine which parameters best discriminated outcome among pediatric patients with intermediate-risk rhabdomyosarcoma (RMS). METHODS: Complete information was available for 370 patients with nonmetastatic RMS who were enrolled in the Children's Oncology Group (COG) intermediate-risk study D9803 (1999-2005). The Kaplan-Meier method was used to estimate survival distributions. A recursive partitioning model was used to identify prognostic factors that were associated with event-free survival (EFS). Cox proportional hazards regression models were used to estimate the association between patient characteristics and the risk of failure or death. RESULTS: For all patients with intermediate-risk RMS, a recursive partitioning algorithm for EFS suggested that prognostic groups should be defined optimally by tumor volume (with a transition point at 20 cm(3) ), patient weight (with a transition point at 50 kg), and embryonal histology. Tumor volume and patient weight added significant outcome information to the standard prognostic factors, including greatest tumor dimension and patient age (P = .02). The ability to resect the tumor completely was not associated significantly with the size of the patient, and patient weight did not significantly modify the association between tumor volume and EFS after adjustment for standard risk factors (P = .2). CONCLUSIONS: The factors that had the strongest association with EFS were tumor volume, patient weight, and histology. On the basis of regression modeling, tumor volume and patient weight were superior predictors of outcome compared with greatest tumor dimension and patient age in children with intermediate-risk RMS. The current results indicated that the prognostic performance of tumor volume and patient weight should be assessed in an independent prospective study.


Asunto(s)
Peso Corporal , Rabdomiosarcoma/epidemiología , Carga Tumoral , Adolescente , Factores de Edad , Niño , Preescolar , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Estadificación de Neoplasias , Pronóstico , Rabdomiosarcoma/patología , Rabdomiosarcoma/terapia , Riesgo , Análisis de Supervivencia
14.
J Clin Oncol ; 28(30): 4658-63, 2010 Oct 20.
Artículo en Inglés | MEDLINE | ID: mdl-20837952

RESUMEN

PURPOSE: To compare response rates for two schedules of irinotecan with vincristine in patients with rhabdomyosarcoma at first relapse or disease progression. PATIENTS AND METHODS: Patients with first relapse or progression of rhabdomyosarcoma and an unfavorable prognosis were randomly assigned to one of two treatment schedules of irinotecan with vincristine: regimen 1A included irinotecan 20 mg/m(2)/d intravenously for 5 days at weeks 1, 2, 4, and 5 with vincristine 1.5 mg/m(2) administered intravenously on day 1 of weeks 1, 2, 4, and 5; regimen 1B included irinotecan 50 mg/m(2)/d intravenously for 5 days at weeks 1 and 4 with vincristine as in regimen 1A. Disease response was assessed at week 6. Those with responsive disease continued to receive 44 weeks of multiagent chemotherapy that incorporated the assigned irinotecan-vincristine regimen. RESULTS: Ninety-two eligible patients were randomly assigned (1A, 45; 1B, 47). Response could be assessed in 89 patients (1A, 42; 1B, 47). There were five complete responses and six partial responses on regimen 1A (response rate, 26%; 95% CI, 16% to 42%) and 17 partial responses on regimen 1B (response rate, 37%; 95% CI, 25% to 51%; P = .36). Neutropenia was less common on regimen 1A (P = .04). One-year failure-free and overall survival rates for regimen 1A were 37% (95% CI, 23% to 51%) and 55% (95% CI, 39% to 69%), respectively, and for 1B, they were 38% (95% CI, 25% to 53%) and 60% (95% CI, 44% to 72%). CONCLUSION: There was no difference in the response rates between the two irinotecan-vincristine schedules. We recommend the shorter, more convenient regimen (1B) for further investigation.


Asunto(s)
Protocolos de Quimioterapia Combinada Antineoplásica/administración & dosificación , Rabdomiosarcoma/tratamiento farmacológico , Protocolos de Quimioterapia Combinada Antineoplásica/efectos adversos , Camptotecina/administración & dosificación , Camptotecina/análogos & derivados , Niño , Progresión de la Enfermedad , Supervivencia sin Enfermedad , Esquema de Medicación , Femenino , Humanos , Irinotecán , Estimación de Kaplan-Meier , Masculino , Recurrencia , Factores de Riesgo , Factores de Tiempo , Resultado del Tratamiento , Estados Unidos , Vincristina/administración & dosificación
15.
Fetal Pediatr Pathol ; 28(6): 262-73, 2009.
Artículo en Inglés | MEDLINE | ID: mdl-19842881

RESUMEN

A case of pleuropulmonary blastoma in a 13-year-old child, exposed to the Chernobyl disaster while in-utero, is presented and discussed by both clinician and pathologist, in this traditional clinical-pathologic conference. The discussion includes the differential diagnoses of chest mass in children.


Asunto(s)
Neoplasias Pulmonares/diagnóstico , Blastoma Pulmonar/diagnóstico , Neoplasias Torácicas/diagnóstico , Adolescente , Quimioterapia Adyuvante , Terapia Combinada , Diagnóstico Diferencial , Resultado Fatal , Humanos , Neoplasias Pulmonares/cirugía , Neoplasias Pulmonares/terapia , Masculino , Neumonectomía , Blastoma Pulmonar/cirugía , Blastoma Pulmonar/terapia , Radioterapia Adyuvante , Neoplasias Torácicas/cirugía , Neoplasias Torácicas/terapia , Tomografía Computarizada por Rayos X
16.
J Pediatr Surg ; 44(9): 1812-6, 2009 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-19735830

RESUMEN

PURPOSE: Few studies address the surgical correction of pectus excavatum (PE) in patients with connective tissue disease (CTD). We have identified the preoperative characteristics, postoperative complications, and outcomes of patients with CTD undergoing bar repair of PE and compared these outcomes to a control group without CTD. METHODS: A retrospective review of patients undergoing primary repair of PE with a bar procedure from 1997 to 2006 identified 22 patients with CTD. Of those, 20 (90.9%) had their bars removed. We identified 223 patients of similar age without CTD whose bars were removed. Data collected included demographics, preoperative symptoms, operative characteristics, and postoperative outcomes. RESULTS: Among those with CTD, the median age at repair was 15.5 years, with a mean pectus index of 4.0 +/- 1.4. Three patients (13.6%) experienced bar displacement or upper sternal depression requiring surgical revision. Only 1 patient recurred after bar removal. Rates of bar displacement, upper sternal depression, and recurrence were not statistically different than those in the comparison group. CONCLUSIONS: Patients with CTD benefit from primary bar repair of PE and experience excellent operative outcomes after repair, with complication rates being no different than those found in similarly aged control patients.


Asunto(s)
Enfermedades del Tejido Conjuntivo/cirugía , Tórax en Embudo/cirugía , Prótesis e Implantes , Implantación de Prótesis/métodos , Adolescente , Estudios de Casos y Controles , Femenino , Humanos , Masculino , Complicaciones Posoperatorias , Reoperación , Estudios Retrospectivos , Resultado del Tratamiento , Adulto Joven
17.
J Clin Oncol ; 27(31): 5182-8, 2009 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-19770373

RESUMEN

PURPOSE: The purpose of this study was to compare the outcome of patients with intermediate-risk rhabdomyosarcoma (RMS) treated with standard VAC (vincristine, dactinomycin, and cyclophosphamide) chemotherapy to that of patients treated with VAC alternating with vincristine, topotecan, and cyclophosphamide (VAC/VTC). PATIENTS AND METHODS: Patients were randomly assigned to 39 weeks of VAC versus VAC/VTC; local therapy began after week 12. Patients with parameningeal RMS with intracranial extension (PME) were treated with VAC and immediate x-ray therapy. The primary study end point was failure-free survival (FFS). The study was designed with 80% power (5% two-sided alpha level) to detect an increase in 5-year FFS from 64% to 75% with VAC/VTC. RESULTS: A total of 617 eligible patients were entered onto the study: 264 were randomly assigned to VAC and 252 to VAC/VTC; 101 PME patients were nonrandomly treated with VAC. Treatment strata were embryonal RMS, stage 2/3, group III (33%); embryonal RMS, group IV, less than age 10 years (7%); alveolar RMS or undifferentiated sarcoma (UDS), stage 1 or group I (17%); alveolar RMS/UDS (27%); and PME (16%). At a median follow-up of 4.3 years, 4-year FFS was 73% with VAC and 68% with VAC/VTC (P = .3). There was no difference in effect of VAC versus VAC/VTC across risk groups. The frequency of second malignancies was similar between the two treatment groups. CONCLUSION: For intermediate-risk RMS, VAC/VTC does not significantly improve FFS compared with VAC.


Asunto(s)
Protocolos de Quimioterapia Combinada Antineoplásica/administración & dosificación , Rabdomiosarcoma/tratamiento farmacológico , Niño , Preescolar , Ciclofosfamida/administración & dosificación , Ciclofosfamida/efectos adversos , Dactinomicina/administración & dosificación , Dactinomicina/efectos adversos , Supervivencia sin Enfermedad , Femenino , Humanos , Lactante , Estimación de Kaplan-Meier , Masculino , Estadificación de Neoplasias , Rabdomiosarcoma/mortalidad , Rabdomiosarcoma/patología , Topotecan/administración & dosificación , Topotecan/efectos adversos , Vincristina/administración & dosificación , Vincristina/efectos adversos
18.
J Am Coll Radiol ; 6(8): 551-7, 2009 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-19643382

RESUMEN

Developmental dysplasia of the hip (DDH) affects 1.5 of every 1,000 caucasian Americans and less frequently affects African Americans. Developmental dysplasia of the hip comprises a spectrum of abnormalities, ranging from laxity of the joint and mild subluxation to fixed dislocation. Early diagnosis of DDH usually leads to low-risk treatment with a harness. Late diagnosis of DDH in children may lead to increased surgical intervention and complications. Late diagnosis of DDH in adults can result in debilitating end-stage degenerative hip joint disease. Screening decreases the incidence of late diagnosis of DDH. Clinical evaluation for DDH should be performed periodically at each well-baby visit until the age of 12 months. There is no consensus on imaging screening for DDH. Consideration for screening with ultrasound is balanced between the benefits of early detection of DDH and the increased treatment and cost factors. In addition, randomized trials evaluating primary ultrasound screening did not find significant decrease in late diagnosis of DDH. In the United States, hip ultrasound is selectively performed in infants with risk factors, such as family history of DDH, breech presentation, and inconclusive findings on physical examination. Ultrasound for DDH should be performed after 2 weeks of age because laxity is common after birth and often resolves itself. A pelvic radiograph can optimally be performed after the age of 4 months, when most infants will have ossification centers of the femoral heads.


Asunto(s)
Diagnóstico por Imagen/normas , Luxación Congénita de la Cadera/diagnóstico , Tamizaje Masivo/normas , Pediatría/normas , Radiología/normas , Niño , Humanos
19.
Pediatrics ; 123(1): 199-206, 2009 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-19117883

RESUMEN

OBJECTIVE: Traumatic brain injury has a substantial impact on caregivers. This study describes the burden experienced by caregivers of children with traumatic brain injury and examines the relationship between child functioning and family burden during the first year after injury. PATIENTS AND METHODS: Children aged 5 to 15 years hospitalized for traumatic brain injury at 4 participating trauma centers were eligible. Caregivers completed baseline and 3- and 12-month telephone interviews measuring the child's health-related quality of life using the Pediatric Quality of Life Inventory. The emotional impact scale of the Child Health Questionnaire was used to identify caregivers with substantial distress, including general worry or interference with family routine. Caregiver perceptions of whether health care needs were met or unmet and days missed from work were also measured. RESULTS: A total of 330 subjects enrolled; follow-up was conducted with 312 at 3 months and 288 at 12 months. Most subjects were white (68%) and male (69%). Abnormal Pediatric Quality of Life Inventory subscores were related to substantial caregiver burden (either general worry or interference in routine). These abnormalities were reported by >75% of patients at 3 months and persisted to 1 year in some patients. Parental perception of unmet health care needs was strongly related to family burden outcomes, with up to 69% of this subset of parents reporting substantial worry, and nearly one quarter reporting interference with daily routine/concentration 1 year after injury. Child dysfunction predicted parental burden at 3 and 12 months. Burden was greater when health care need was unmet. Abnormalities on the Pediatric Quality of Life Inventory predicted the amount of work missed by parents, especially in the presence of unmet needs. CONCLUSIONS: Caregivers are more likely to report family burden problems when child functioning is poorer and health care needs are unmet. Improved identification and provision of services is a potentially modifiable factor that may decrease family burden after pediatric traumatic brain injury.


Asunto(s)
Lesiones Encefálicas/economía , Lesiones Encefálicas/psicología , Costo de Enfermedad , Familia/psicología , Adolescente , Lesiones Encefálicas/complicaciones , Niño , Preescolar , Femenino , Estudios de Seguimiento , Hospitalización/economía , Humanos , Masculino , Calidad de Vida/psicología
20.
Ann Thorac Surg ; 86(2): 402-8; discussion 408-9, 2008 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-18640305

RESUMEN

BACKGROUND: Although extensive literature exists on the Lorenz bar repair of pectus excavatum (PE) in pediatric patients, few data examine this repair in adults or compare long-term outcomes in adults with the pediatric population. We identified the preoperative characteristics, postoperative complications, and outcomes of adult patients undergoing Lorenz bar repair of PE who had bar removal and compared these outcomes with a pediatric population undergoing the same procedure. METHODS: A retrospective review (1997 to 2006) of patients undergoing primary repair of PE with a Lorenz bar identified 107 individuals aged older than 18 and 137 patients aged 6 to 14, of whom 52 and 80 had their bar(s) removed, respectively. These latter patients were the focus of analysis. Data collected included demographics, preoperative symptoms, operative characteristics, and postoperative outcomes. RESULTS: The median (interquartile range, IQR) age and pectus index of adult patients (81% men) at the time of repair was 23 (18 to 30) years and 3.8 (3.5 to 4.3), respectively. In 2 adults (3.9%), PE recurred after bar removal, and 6 (11.6%) required surgical revision for bar displacement or upper sternal depression. These rates of complications were similar to those found in children undergoing Lorenz bar repair of PE at our institution. CONCLUSIONS: Lorenz bar placement to correct PE in adults can be performed safely and effectively, with rates of bar displacement, sternal depression, recurrence, and reoperation that are not statistically different than those found in a younger pediatric population.


Asunto(s)
Tórax en Embudo/cirugía , Prótesis e Implantes , Adolescente , Adulto , Femenino , Humanos , Tiempo de Internación , Masculino , Complicaciones Posoperatorias/epidemiología , Implantación de Prótesis , Estudios Retrospectivos , Resultado del Tratamiento
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA
...